Ọmụmụ ụlọ ọgwụ na ahụ mmadụ: NMN nwere ike belata ọkwa triglyceride nke ọma

Triglyceride (TG) bụ ụdị abụba nwere nnukwu ọdịnaya n'ime ahụ mmadụ.Akụkụ niile na anụ ahụ nke ahụ mmadụ nwere ike iji triglyceride nye ume, imeju nwere ike ịmepụta triglyceride ma chekwaa ya n'ime imeju.Ọ bụrụ na triglyceride na-abawanye, ọ pụtara na imeju na-akwakọba oke abụba, nke bụ imeju nwere abụba.Triglyceride bụ ụdị hyperlipidemia, isi ihe na-emerụ ahụ mmadụ bụ ịkpata atherosclerosis, mgbochi arịa ọbara na thrombosis.Na mgbakwunye, ọmụmụ egosila na triglycerides dị elu nwekwara ike ibute ọbara mgbali elu, ọrịa gallstones, pancreatitis, ọrịa Alzheimer na ihe ndị ọzọ.

Nnyocha ụlọ ọgwụ mmadụ mere na nso nso a na Japan gosikwara uru NMN bara n'ahụ mmadụ.Site na nnwale ụlọ ọgwụ mmadụ, ndị otu nyocha gosipụtara na ịgba ọgwụ mgbochi nke NMN dị mma maka ahụ mmadụ, nke nwere ike ọ bụghị naanị ịbawanye ọkwa NAD + ọbara nke ukwuu, kamakwa belata ọkwa triglyceride ọbara n'emebighị mkpụrụ ndụ ọbara.

Ndị otu nyocha ahụ wetara ndị ọrụ afọ ofufo 10 ahụike (ụmụ nwoke 5 na ụmụ nwanyị 5, ndị gbara afọ 20 ~ 70).Mgbe o buchara ọnụ maka awa 12, 300mg nke NMN gbazere na saline 100mL wee tinye n'ime ndị ọrụ afọ ofufo site na vein ogwe aka (5mL / min).A na-ewere ụzarị ọkụ nke obi tupu na mgbe ịgbanye NMN, ma tụọ ịdị arọ, okpomọkụ, ọbara mgbali elu, pulse na ọbara oxygen saturation.A na-anakọta ọbara na mmamịrị maka nnwale.Site na nyocha ntụnyere nke ọtụtụ nsonaazụ ule, a chọpụtara na isi ihe nrịbama nke imeju, pancreas, obi na akụrụ enweghị mgbanwe doro anya, na mgbakwunye, ha agaghị emetụta isi ihe nrịbama nke mkpụrụ ndụ ọbara uhie, mkpụrụ ndụ ọbara ọcha. na platelet n'ime ọbara, ndị so na ya enweghị mmeghachi omume ọjọọ.

Ọ dị mma ịmara na ọkwa nke triglyceride n'ọbara agbanweela n'ụzọ doro anya.Mgbe isiokwu ndị ahụ natara ọgwụ NMN maka ọkara elekere, ọkwa nke triglyceride dara n'ụzọ doro anya, ruo mgbe awa 5 gachara, n'agbanyeghị na enwere obere mgbake, ọdịiche a dị ịrịba ama ka dị.

Site na nnwale anụmanụ nke izizi ruo na nnwale ụlọọgwụ mmadụ, enyochala uru NMN nwere maka ahụ mmadụ nke ọma.Ọmụmụ ụlọ ọgwụ mmadụ a na-egosi ọrụ NMN na-ebelata triglyceride, nke bụ ozi ọma maka ndị buru ibu na ndị agadi.

Ntụaka:
[1].Kimura S, Ichikawa M, Sugawara S, et al.(Septemba 05, 2022) Nicotinamide Mononucleotide bụ metabolized nke ọma ma na-ebelata ọkwa triglyceride ọbara n'otu n'otu nwere ahụike.Cureus 14 (9): e28812.doi:10.7759/cureus.28812