Triglyceride (TG) bụ ụdị abụba nwere nnukwu ihe dị n'ahụ mmadụ. Akụkụ ahụ na anụ ahụ niile nke mmadụ nwere ike iji triglyceride nye ike, imeju nwekwara ike imepụta triglyceride ma chekwaa ya n'ime imeju. Ọ bụrụ na triglyceride amụbaa, ọ pụtara na imeju na-agbakọta oke abụba, nke bụ imeju abụba. Triglyceride bụ ụdị hyperlipidemia, ihe kachasị emerụ ahụ mmadụ bụ atherosclerosis, mkpọchi arịa ọbara na thrombosis. Na mgbakwunye, ọmụmụ ihe egosila na oke triglyceride nwekwara ike ibute ọbara mgbali elu, nkume gallstone, pancreatitis, ọrịa Alzheimer na ndị ọzọ.
Nnyocha ahụike mmadụ mere n'oge na-adịbeghị anya na Japan gosikwara uru nke NMN bara n'ahụ mmadụ. Site na nnwale ahụike mmadụ, ndị otu nyocha ahụ gosipụtara na ịgba NMN n'ime akwara dị mma maka ahụ mmadụ, nke nwere ike ọ bụghị naanị ịbawanye ọkwa NAD+ dị n'ọbara, kamakwa belata ọkwa triglyceride dị n'ọbara n'emebighị mkpụrụ ndụ ọbara.
Ndị otu nnyocha ahụ kpọbatara mmadụ iri nwere ahụ ike (ụmụ nwoke ise na ụmụ nwanyị ise, dị afọ 20 ruo 70). Mgbe ha busịrị ọnụ ruo awa iri na abụọ, a gbazere 300mg nke NMN na nnu 100mL ma gbanye ya n'ime ndị ọrụ afọ ofufo site na akwara aka (5mL/min). E were X-ray obi tupu na mgbe a gbanyere NMN, a tụkwara ibu, okpomọkụ, ọbara mgbali elu, obi na oke oxygen njupụta n'ọbara. A chịkọtara ọbara na mmamịrị maka nnwale. Site na nyocha ntụnyere nke ọtụtụ nsonaazụ nnwale, achọpụtara na ihe nrịbama bụ isi nke imeju, pancreas, obi na akụrụ enweghị mgbanwe doro anya, na mgbakwunye, ha agaghị emetụta ihe nrịbama bụ isi nke mkpụrụ ndụ ọbara uhie, mkpụrụ ndụ ọbara ọcha na platelet n'ọbara, ndị sonyere na-enwekwaghị mmeghachi omume ọjọọ.
Ọ dị mkpa ịmara na ọkwa triglyceride dị n'ọbara agbanweela nke ọma. Mgbe ndị a gbara ọgwụ NMN ruo ọkara awa, ọkwa triglyceride dara nke ọma, ruo awa ise ka e mesịrị, ọ bụ ezie na enwere obere usoro mgbake, nnukwu ọdịiche a ka dị.
Site na nnwale anụmanụ tupu a mụọ nwa ruo na nnwale ahụike mmadụ, uru nke NMN bara n'ahụ mmadụ ka egosipụtala nke ọma. Ọmụmụ ihe ahụike mmadụ a na-egosi ọrụ NMN na ibelata triglyceride, nke bụ ozi ọma maka ndị buru ibu na ndị agadi.
Ntụaka:
[1]. Kimura S, Ichikawa M, Sugawara S, et al. (Septemba 05, 2022) A na-agbanwe Nicotinamide Mononucleotide n'enweghị nsogbu ma na-ebelata ọkwa triglyceride ọbara n'ime ndị nwere ahụike nke ukwuu. Cureus 14(9): e28812. doi:10.7759/cureus.28812
Oge ozi: Nọvemba-11-2022