β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd bụ onye na-emepụta ihe na onye na-ebubata β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS: 53-59-8) nwere oke mma.Anyị nwere ike ịnye COA, nnyefe zuru ụwa ọnụ, obere na nnukwu ọnụọgụ dị.Ọ bụrụ na ị nwere mmasị na ngwaahịa a, biko ziga ozi zuru ezu gụnyere nọmba CAS, aha ngwaahịa, ọnụ ọgụgụ anyị.Biko kpọtụrụ:lchen@syncozymes.com
| Aha Chemical | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Ụdị okwu | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Nọmba CAS | 53-59-8 |
| Ibu molekụla | 743.41 |
| Usoro ihe omimi | C21H28N7O17P3 |
| EINECS Mba. | 200-178-1 |
| nchekwa okpomọkụ. | Debe n'ebe gbara ọchịchịrị, ikuku na-adịghị mma, chekwaa na friza, n'okpuru -20 Celsius |
| solubility | H2O: 50 mg / ml, doro anya, ntakịrị odo odo |
| pka | pKa1 3.9;pKa2 6.1 (na 25 ℃) |
| kacha | 260nm (ọkụ) |
| Merck | 14,6348 |
| Sistemụ ndekọ ihe EPA | Adenosine 5'- (trihydrogen diphosphate), 2'- (dihydrogen phosphate), P'.fwdarw.5'-ester na 3- (aminocarbonyl) -1-.beta.-D-ribofuranosylpyridinium, nnu n'ime (53-59- 8) |
| Nwale ihe | Nkọwapụta |
| Ọdịdị | White ka odo ntụ ntụ |
| Solubility | 200mg / ml na mmiri |
| Uru pH (100mg/ml) | 5.0-7.0 |
| Nyocha UV Spectral 260 nm na pH 7.5 | (18±1.0)×10³L/mol/cm |
| Ọdịnaya (site na nyocha enzymatic na G6PDH na pH 7.5, na-eji spectrophotometer, abs.340nm, na ndabere anhydrous) | ≥90.0% |
| Ịdị ọcha (nke HPLC,% mpaghara) | ≥95.0% |
| Ọdịnaya mmiri (nke KF) | ≤5% |
ngwugwu:Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Debe nke ọma na ọchịchịrị, maka nchekwa ogologo oge, debe ya na 2 ~ 8 ℃.
NADP bụ coenzyme, nke bụ ihe nke nicotinamide adenine dinucleotide na molecule phosphate na-ejikọta ester bond, ma dị ebe niile.na ndu ndu.Njirimara kemịkalụ ya, ụdị nnabata, ụdị redox, wdg yiri NAD (Coenzyme I).Enwere ike iji NADP mee ihe n'ọtụtụ ebe na mmeghachi omumedehydrogenases mmanya dị iche iche, ketoreductases na oxidoreductases ndị ọzọ na-abawanye.Dị ka: ọ nwere ike belata na NADPH site na ọtụtụ dehydrogenases dị otú ahụdị ka 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44).Otú ọ dị, ọ bụchaghị na ọ ga-enwe ike imeghachi omume n'ọtụtụ mmadụdehydrogenases na-eji NAD, ma ọ bụ enweghị ike ime ya ozugbo site na yinye iku ume.N'adịghị ka NAD, ọ na-adị tumadi na ọnọdụ mbelata na sel nke ihe ndị dị ndụ aerobic.
Dịka ojiji ngwaahịa si dị, enwere ike kewaa ya n'ime akara ule ndị a: ọkwa biotransformation, ọkwa reagent diagnostic, ọkwa nri ahụike.
Ọkwa biotransformation: Enwere ike iji ya maka njikọ nke intermediates ọgwụ na API, tumadi na enzymes catalytic, dị ka ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), glucose dehydrogenase (GDH), wdg. Chere.
Ọkwa reagent nchọpụta: Site na ọtụtụ enzymes nchoputa, dị ka akụrụngwa nke ngwa nyocha.
Ọkwa nri ahụike: Ngwa mgbakwunye nri nke NADP bụ ọkachasị na usoro nyocha na mmepe.
