β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd. bụ onye nrụpụta na onye na-eweta β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS:53-59-8) nke nwere ogo dị elu. Anyị nwere ike inye COA, nnyefe zuru ụwa ọnụ, obere na nnukwu ọnụọgụ dị. Ọ bụrụ na ị nwere mmasị na ngwaahịa a, biko zitere anyị ozi zuru ezu gụnyere nọmba CAS, aha ngwaahịa, na ọnụọgụ. Biko kpọtụrụ:lchen@syncozymes.com
| Aha Kemịkal | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Okwu ndị yiri ya | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Nọmba CAS | 53-59-8 |
| Ibu Molekụla | 743.41 |
| Usoro Molekụla | C21H28N7O17P3 |
| Nọmba EINECS | 200-178-1 |
| okpomọkụ nchekwa. | Debe n'ebe gbara ọchịchịrị, ebe na-anaghị ekpo ọkụ, Debe na friza, n'okpuru -20°C |
| mgbaze | H2O: 50 mg/mL, doro anya, odo odo ntakịrị |
| pka | pKa1 3.9; pKa2 6.1(na 25℃) |
| λmax | 260nm (ọkụ) |
| Merck | 14,6348 |
| Sistemụ Ndebanye Ihe EPA | Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'.fwdarw.5'-ester nwere 3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, nnu dị n'ime (53-59-8) |
| Ihe Nnwale | Nkọwapụta |
| Ọdịdị | Ntụ ntụ ọcha ruo odo odo |
| Mmiri na-agbaze | 200mg/ml n'ime mmiri |
| Uru pH (100mg/ml) | 5.0~7.0 |
| Nyocha UV Spectral εat 260 nm na pH 7.5 | (18±1.0) ×10³L/mol/cm |
| Ọdịnaya (site na nyocha enzymatic na G6(PDH na pH 7.5, site na iji spectrophotometer, abs.340nm, dabere na mmiri anaghị agbaze) | ≥90.0% |
| Ịdị ọcha (site na HPLC, %mpaghara) | ≥95.0% |
| Mmiri dị n'ime ya (site na KF) | ≤5% |
Ngwugwu:Karama, akpa foil Aluminom, 25kg/Kaadọn Drum, ma ọ bụ dịka ihe onye ahịa chọrọ si dị.
Ọnọdụ Nchekwa:Debe ya n'ime ebe gbara ọchịchịrị, debe ya na okpomọkụ nke 2-8 ℃ maka nchekwa ogologo oge.
NADP bụ coenzyme, nke bụ ihe e ji njikọ ester kekọta nicotinamide adenine dinucleotide na molekul phosphate, ma dịkwa ọtụtụ ebe.n'ụwa ihe ndị dị ndụ. Njirimara kemịkalụ ya, ụdị absorption, ụdị redox, wdg. yiri NAD (Coenzyme I). Enwere ike iji NADP mee ihe nke ọma na mmeghachi omume.ihe ndị na-eme ka mmanya na-egbu egbu dị iche iche, ketoroductases na oxidoreductases ndị ọzọ na-akpali ya. Dịka ọmụmaatụ: enwere ike ibelata ya ka ọ bụrụ NADPH site na ọtụtụ dehydrogenases dị kadị ka 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44). Agbanyeghị, ọ bụghị ya nwere ike imeghachi omume na ọtụtụdehydrogenases ndị na-eji NAD eme ihe, ọ dịghịkwa ekwe ka usoro iku ume mee ka ọ dị oxidized ozugbo. N'adịghị ka NAD, ọ na-adịkarị n'ọnọdụ dị ala na mkpụrụ ndụ nke ihe ndị dị ndụ aerobic.
Dịka ojiji ngwaahịa si dị, enwere ike kewaa ya n'ime akara ndị a: ọkwa biotransformation, ọkwa ihe nchọpụta ọrịa, ọkwa nri ahụike.
Ọkwa mgbanwe bio: Enwere ike iji ya maka njikọta nke ndị na-emepụta ọgwụ na API, ọkachasị site na enzymes catalytic, dị ka ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), glucose dehydrogenase (GDH), wdg. Chere.
Ọkwa ihe nchọpụta ọrịa: Site na ọtụtụ enzymes nchọpụta ọrịa, dị ka ihe e ji eme ihe na ngwa nchọpụta ọrịa.
Ọkwa nri ahụike: Iji mgbakwunye nri nke NADP eme ihe bụ isi n'usoro nyocha na mmepe.
