β- Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Nnu (ụdị ebelatara) (NADPH)
NADPH bụ ihe e ji phosphorylated mepụta nke nicotinamide adenine dinucleotide (NAD) na ọnọdụ 2' nke ribose ring system jikọtara ya na adenine ma na-etinye aka na mmeghachi omume anabolic dị iche iche,dịka njikọta nke lipids, fatty acids na nucleotides. Mmeghachi omume ndị a chọrọ NADPH dị ka ihe na-ebelata ihe na onye na-enye hydride.
Dịka ojiji ngwaahịa si dị, enwere ike kewaa ya n'ime ọkwa ndị a: ọkwa biotransformation, ọkwa reagent diagnostic.
Ọkwa mgbanwe bio: Enwere ike iji ya mee ihe maka njikọta nke ọgwụ etiti na API, ọkachasị site na ijikọ ya na enzymes catalytic. Ugbu a, a na-eme nnyocha ya karịsịa n'ọkwa ụlọ nyocha.
Ọkwa ihe nchọpụta ọrịa: A na-eji ya na ọtụtụ enzymes nchọpụta dị iche iche dịka ihe e ji arụ ọrụ na ngwa nchọpụta ọrịa.
Uru ahịa anyị bara
① Nhazi ihe ndị dị ndụ, nchekwa akwụkwọ ndụ na gburugburu ebe obibi, dịka iwu nchekwa gburugburu ebe obibi dị ugbu a n'ụlọ na mba ofesi si dị.
② Ọnụ ego dị ala na ọnụ ahịa ire ere bara uru.
③ Inye ngwaahịa siri ike, nnyefe ngwaahịa ogologo oge.
| Aha Kemịkal | NADPH |
| Okwu ndị yiri ya | β- Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Nnu (ụdị ebelatara) |
| Nọmba CAS | 2646-71-1 |
| Ibu Molekụla | 769.42 |
| Usoro Molekụla | C21H31N7NaO17P3 |
| EINECS gụnyere: | 220-163-3 |
| Ebe agbaze | >250°C (nkeji iri na abụọ) |
| okpomọkụ nchekwa. | Debe n'ebe gbara ọchịchịrị, ebe na-anaghị ekpo ọkụ, Debe na friza, n'okpuru -20°C |
| mgbaze | 10 mM NaOH: agbaze 50mg/mL, doro anya |
| ụdị | Ntụ ntụ |
| agba | Ọcha ruo Ọcha dị ọcha |
| Merck | 14,6348 |
| Nkwụsi ike nke mmiri: | Na-agbaze n'ime mmiri (50 mg/ml). |
| Mmetụta | Mmetụta Dị Mfe |
| Ihe Nnwale | Nkọwapụta |
| Ọdịdị | Ntụ ntụ ọcha ruo odo odo |
| Ịdị ọcha (site na HPLC, %mpaghara) | ≥90.0% |
| Mmiri dị n'ime ya (site na KF) | Kpesa maka ozi |
Ngwugwu:Karama, akpa foil Aluminom, 25kg/Kaadọn Drum, ma ọ bụ dịka ihe onye ahịa chọrọ si dị.
Ọnọdụ Nchekwa:Debe ya nke ọma n'ime ebe gbara ọchịchịrị n'okpuru -15 ℃.
NADPH bụ ihe e ji phosphorylated mee nke dị n'ọnọdụ 2' nke sistemụ ribose ring jikọtara ya na adenine na nicotinamide adenine dinucleotide (NAD), nke na-esonye n'ọtụtụ mmeghachi omume anabolic, dịka njikọta nke lipids, fatty acids na nucleotides. N'ime mmeghachi omume ndị a, a chọrọ NADPH dị ka ihe na-ebelata ihe na onye na-enye anion.
Enwere ike iji ya mee ihe maka imepụta ihe ndị na-eme ka ọgwụ dị n'etiti ọgwụ na ihe ndị e ji arụ ọrụ, ọkachasị na njikọta ya na enzymes catalytic, a na-amụkwa ya ugbu a na ụlọ nyocha.
