β-Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Nnu (ụdị belatara) (NADPH)
NADPH bụ ihe phosphorylated nke nicotinamide adenine dinucleotide (NAD) na 2'-ọnọdụ nke usoro mgbanaka ribose jikọtara adenine ma na-etinye aka na mmeghachi omume anabolic dị iche iche,dị ka njikọ nke lipids, fatty acids na nucleotides.Mmeghachi omume ndị a chọrọ NADPH dị ka onye na-ebelata ihe na onye na-enye hydride.
Dịka ojiji ngwaahịa si dị, enwere ike kewaa ya n'ime akara ule ndị a: ọkwa biotransformation, diagnostic reagent ọkwa.
Ọkwa biotransformation: Enwere ike iji ya maka njikọ nke etiti ọgwụ na API, tumadi site na imekọ ihe ọnụ na enzymes catalytic.Ugbu a, a na-enyocha ya nke ọma na ọkwa ụlọ nyocha.
Ọkwa reagent nchọpụta: A na-eji ọtụtụ enzymes achọpụta ọrịa dị ka akụrụngwa nke ngwa nyocha.
Uru ahịa anyị
① Nkwekọrịta nke ndu, nchekwa ndụ ndụ na gburugburu ebe obibi, kwekọrọ na ihe nchekwa gburugburu ebe obibi ugbu a chọrọ n'ụlọ na ná mba ọzọ.
② Ọnụ ala dị ala yana ọnụ ahịa ire ere.
③ ọkọnọ kwụsiri ike, ọkọnọ ngwaahịa ogologo oge.
Aha Chemical | NADPH |
Ụdị okwu | β-Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Nnu (ụdị belatara) |
Nọmba CAS | 2646-71-1 |
Ibu molekụla | 769.42 |
Usoro ihe omimi | C21H31N7NaO17P3 |
EINECS gụnyere: | 220-163-3 |
Ebe mgbaze | > 250°C (dec.) |
nchekwa okpomọkụ. | Debe n'ebe gbara ọchịchịrị, ikuku na-adịghị mma, chekwaa na friza, n'okpuru -20 Celsius |
solubility | 10 mM NaOH: soluble50mg/ml, doro anya |
ụdị | Ntụ ntụ |
agba | Ọcha ka Gbanyụọ-ọcha |
Merck | 14,6348 |
Nkwụsi ike mmiri: | Soluble na mmiri (50 mg / ml). |
Mmetụta | Ìhè nwere mmetụta |
Nwale ihe | Nkọwapụta |
Ọdịdị | White ka odo ntụ ntụ |
Ịdị ọcha (nke HPLC,% mpaghara) | ≥90.0% |
Ọdịnaya mmiri (nke KF) | Kpọọ maka ozi |
ngwugwu:Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Debe nke ọma n'ime ọchịchịrị n'okpuru -15 ℃.
NADPH bụ ihe nrụpụta phosphorylated na 2'- ọnọdụ nke usoro mgbanaka ribose jikọtara adenine na nicotinamide adenine dinucleotide (NAD), nke na-ekere òkè n'ọtụtụ mmeghachi omume anabolic, dị ka njikọ nke lipids, fatty acids na nucleotides.Na mmeghachi omume ndị a, a chọrọ NADPH dị ka onye na-ebelata ego na onye na-enye anion.
Enwere ike iji ya maka njikọ nke intermediates ọgwụ na akụrụngwa akụrụngwa, ọkachasị yana njikọta na enzymes catalytic, a na-amụkwa ya ugbu a na ụlọ nyocha.