β-Nicotinamide Mononucleotide (NMN)
N'oge na-adịbeghị anya, enwere ozi ọma n'ọhịa nke NMN - mgbe nyochachara nke ọma site na kọmitii ọkachamara nke US Food and Drug Administration (FDA) ikike nzukọ, NMN akụrụngwa nke Shangke Biopharmaceutical (Shanghai) Co., Ltd. (nke a na-ekwu banyere ya). dị ka "Shangke Bio") na-akwado site na United States FDA NDI nkwado na-akwado na ya NMN akụrụngwa nwere ike eze na-eji na mmepụta, ahịa na nkwalite nke dietary Mmeju na United States, na ike ịhụ na FDA ukara. webụsaịtị dị ka ngwa mgbakwunye nri ọhụrụ, nọmba 1247.
FDA NDI bụ usoro asambodo kacha mkpa na ahịa US.Inweta asambodo a abụghị naanị pụtara na nchekwa na ogo ngwaahịa Shangke Bio bụnke a ghọtara nke ọma, mana ọ na-akwadokwa mmepe ahaziri ahazi nke ụlọ ọrụ NMN n'ikpeazụ.
Aha Chemical | β-Nicotinamide Mononucleotide |
Ụdị okwu | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE |
Nọmba CAS | 1094-61-7 |
Ibu molekụla | 334.22 |
Usoro ihe omimi | C11H15N2O8P |
EINECS gụnyere: | 214-136-5 |
Ebe mgbaze | 166 Celsius C (dc.) |
nchekwa okpomọkụ. | -20°C |
solubility | DMSO (obere, ekpo ọkụ), methanol (obere), mmiri (obere) |
ụdị | siri ike |
agba | Ọcha na-acha odo odo |
Merck | 13,6697 |
BRN | 3570187 |
Nkwụsi ike: | Ezigbo hygroscopic |
InChiKey | DAYLJWODMCOQEW-TURQNECASA-N |
Nwale Ihe | Nkọwapụta |
Ọdịdị | Uzuzu crystalline ọcha ruo na-acha ọcha |
Ọdịnaya sodium | ≤1% |
Uru pH (100mg/ml) | 2.0-4.0 |
Ịdị ọcha | ≥99.0% |
Ọdịnaya mmiri | ≤1% |
Ọla dị arọ | <10ppm |
Arsenic | <0.5pm |
Ndu | <0.5pm |
Mercury | <0.1pm |
Cadmium | <0.5pm |
Ihe fọdụrụ mgbaze | Ethanol ≤1000ppm |
Ngụkọta ọnụ ọgụgụ microbial ikuku | <750cfu/g |
Yist & ebu | <25cfu/g |
Mkpokọta coliform | ≤0.92MPN/g |
E. Coli | Ihe ọjọọ |
Salmonella | Ihe ọjọọ |
Staph.Aureus | Ihe ọjọọ |
Nnwale (na anhydrous ndabere) | ≥99.0% |
Ọnụọgụ nfe | ≥95% |
Nnukwu njupụta | Kpọọ maka ozi |
ngwugwu:Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Chekwaa n'ime akpa siri ike, nke na-enweghị ọkụ, maka nchekwa ogologo oge, debe ya na 2 ~ 8 Celsius C ma ọ bụ n'okpuru.
Nicotinamide Mononucleotide (NMN) bụ ụdị ọhụrụ nke vitamin B3 nke bụ nzọụkwụ mbụ na NAD + (Nicotinamide Adenine Dinucleotide).NMN bụ onye na-eweghachi NAD + ekwentị mbụ ka egosipụtara na ọ dị irè iji weghachi sel na vivo.
Nicotinamide Adenine Dinucleotide (NAD) bụ otu n'ime ụmụ irighiri ihe dị mkpa na nke na-adọrọ mmasị na ahụ.A na-achọrọ maka mmeghachi omume enzymatic 500 ma na-arụ ọrụ dị mkpa na nhazi nke ihe fọrọ nke nta ka ọ bụrụ usoro usoro ndu niile (Ansari na Raghava, 2010).Karịsịa, ọ nwere ike inye anyị ohere ibi ndụ ahụike na ogologo ndụ.
Nicotinamide Adenine Dinucleotide (NAD) dị n'ụdị oxidized (NAD+) ma ọ bụ ụdị mbelata (NADH), bụ ndị na-akwado ọtụtụ oxidases.
SyncoZyems dị ka onye mbụ nwetara ụlọ ọrụ mmepụta ihe akụrụngwa FDA NDI NMN kwadoro, na-anọchite anya onye ọrụ FDA na-anabata NMN dịka ụdị ihe ọhụrụ nwere ike ịmalite ịnakwere ma kwadoro maka ihe mgbakwunye nri na United States.