Ene reductase (ERED)
ES-ERED na-akwalite ụdị mkpụrụ dị iche iche n'ihi ụdị dị iche iche nke mkpụrụ osisi.N'ozuzu, C = C nke α, β-unsaturated ogige na electron-absorbing otu (gụnyere ketone aldehyde, nitro otu, carboxylic acids, esters, anhydride, lactones, imines, wdg) na-adị mfe belata site ES-ERED, ma. na unactivated abụọ agbụ bụghị.
Enwere ụdị 46 nke ngwaahịa enzyme ERED (Ọnụ ọgụgụ dị ka ES-ERED-101~ES-ERED-146) nke SyncoZymes mepụtara.
Usoro catalytic:
| Enzymes | Koodu ngwaahịa | Nkọwapụta |
| Enzyme ntụ ntụ | ES-ERED-101~ ES-ERED-146 | Otu 46 Ene Reductases, 50 mg nke ọ bụla 46 ihe * 50mg / ihe, ma ọ bụ ọnụọgụ ndị ọzọ. |
| Ngwa nyocha (SynKit) | ES-ERED-4600 | Otu 46 Ene Reductases, 50 mg nke ọ bụla 46 ihe * 50mg / ihe, ma ọ bụ ọnụọgụ ndị ọzọ. |
★ High mkpụrụ Specificity.
★ Strong chiral selectivity.
★ Ntughari dị elu.
★ Obere site-ngwaahịa.
★ Ọnọdụ mmeghachi omume dị nro.
★ enyi na gburugburu ebe obibi.
★ Nchekwa dị elu.
Dị ka ọ na-adịkarị, usoro mmeghachi omume kwesịrị ịgụnye mkpụrụ, ihe nchekwa nchekwa (pH mmeghachi omume kacha mma), coenzymes (NAD (H) ma ọ bụ NADP (H)), sistemụ nrụpụta coenzyme (dịka glucose na glucose dehydrogenase) na ES-ERED.
Enwere ike ịnwale ES-ERED niile n'otu n'otu na sistemụ mmeghachi omume dị n'elu ma ọ bụ jiri ngwa nyocha ERED (SynKit ERED).
➢ Ụdị ES-ERED niile dabara na ọnọdụ mmeghachi omume dị iche iche kwesịrị ka a mụọ ya n'otu n'otu.
➢ Ngwakọta itinye uche dị elu ma ọ bụ ngwaahịa nwere ike igbochi ọrụ ES-ERED.Agbanyeghị, enwere ike belata ihe mgbochi ahụ site na mgbakwunye nke mkpụrụ osisi.
Ọmụmaatụ 1 (α, β-unsaturated aldehydes ma ọ bụ ketones)(1):
Ọmụmaatụ 2(α, β-unsaturated carboxylic acids na ihe ha si pụta)(2):
Debe afọ 2 n'okpuru -20 ℃.
Ejila ọnọdụ dị oke egwu na-akpakọrịta dị ka: oke okpomọkụ, elu / ala pH na nnukwu ihe mgbaze organic.
1. Lucídio C, Fardelone J, Augusto R, na Tal.J.Mol.Catal.B:Ezim., 2004, 29: 41-45.
2. Stueckler C, Ụlọ Nzukọ M, Ehammer H, na Tal..Org.Lett, 2007, 9 (26): 5409-5411.
