Amine Dehydrogenase (AmDH)
Nkọwa dị mkpirikpi:
Banyere Amine Dehydrogenase
ES-AmDH (Amine Dehydrogenase): enzyme nke nwere ike ime ka amoniation nke otu carbonyl belata ma belata ya na otu amino.Ọ bụ coenzyme NADH na-adabere na enzyme, na NADH na-arụ ọrụ dị ka onye na-ebugharị hydrogen.Enwere ụdị 4 nke ngwaahịa enzyme AmDH (Ọnụ ọgụgụ dị ka ES-AmDH101～ES-AmDH104) nke SyncoZymes mepụtara, nke enwere ike iji mee ihe na regioselective ma ọ bụ stereoselective reductive amination nke aldehydes na ketones.
Ụdị mmeghachi omume catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
★ High mkpụrụ Specificity.
★ Strong chiral selectivity.
★ Ntughari dị elu.
★ Obere site-ngwaahịa.
★ Ọnọdụ mmeghachi omume dị nro.
★ enyi na gburugburu ebe obibi.
Dị ka ọ na-adịkarị, sistemu mmeghachi omume kwesịrị ịgụnye mkpụrụ, ngwọta nchekwa, enzyme, coenzyme na sistemụ nrụpụta coenzyme (dịka glucose na glucose dehydrogenase).
➢ AmDH kwesịrị ịgbakwunye ikpeazụ n'ime sistemụ mmeghachi omume, mgbe emezigharịrị pH na ọnọdụ okpomọkụ ka ọ bụrụ ọnọdụ mmeghachi omume.
Ọmụmaatụ 1 (Nkọwa nke chiral amines kwekọrọ site na mbelata amination nke alkyl aryl ketones)(1):
Debe afọ 2 n'okpuru -20 ℃.
Ejila ọnọdụ dị oke egwu na-akpakọrịta dị ka: oke okpomọkụ, elu / ala pH na nnukwu ihe mgbaze organic.
1. Kong W, Liu Y, Huang C, et al.Angewandte Chemie International Edition, 2022: e202202264.
