Ketoreductase (KRED)
KRED sitere na SyncoZymes: Enwere ụdị 191 nke ngwaahịa enzyme KRED (Ọnụ ọgụgụ dị ka ES-KRED-101 ~ ES-KRED-291) nke SyncoZymes mepụtara.Enwere ike iji SZ-KRED mee ihe na regio- na stereoselective mbelata nke aldehydes, beta-ketone esters, α-ketone esters na ketones.
Ụdị mmeghachi omume catalytic:
| Enzymes | Koodu ngwaahịa | Nkọwapụta |
| Enzyme ntụ ntụ | Enzyme ntụ ntụ | Otu 187 Ketoreductases, 50 mg nke ọ bụla 187 ihe * 50mg / ihe, ma ọ bụ ọnụọgụ ndị ọzọ. |
| Ngwa nyocha (SynKit) | ES-KRED-18100 | 181 Ketoreductases, 1 mg kwa 181 ihe * 1 mg / ihe. |
★ High mkpụrụ Specificity.
★ Strong chiral selectivity.
★ High akakabarede arụmọrụ.
★ Obere site-ngwaahịa.
★ Ọnọdụ mmeghachi omume dị nro.
★ enyi na gburugburu ebe obibi.
➢ Ekwesịrị ịme nyocha nke enzyme maka mkpụrụ osisi a kapịrị ọnụ n'ihi nkọwapụta mkpụrụ, wee nweta enzyme nke na-eme ka mkpụrụ nke ebumnuche na-eji mmetụta catalytic kacha mma.
➢ Ya adịla mgbe ị na-akpakọrịta na oke ọnọdụ dị ka: elu okpomọkụ, elu / ala pH na organic mgbaze na elu itinye uche.
Dị ka ọ na-adịkarị, sistemu mmeghachi omume kwesịrị ịgụnye mkpụrụ, ihe nchekwa nchekwa, coenzymes (NAD (H) ma ọ bụ NADP (H)), sistemụ nrụpụta coenzyme (dịka glucose na glucose dehydrogenase).
➢ KRED kwesịrị ịgbakwunye ikpeazụ n'ime sistemụ mmeghachi omume, mgbe emezigharịrị pH na ọnọdụ okpomọkụ ka ọ bụrụ ọnọdụ mmeghachi omume.
➢ KRED dị iche iche nwere ọnọdụ mmeghachi omume dị iche iche, yabụ ekwesịrị ịmụba nke ọ bụla n'ime ha n'otu n'otu.
Ọmụmaatụ 1(1):
Ọmụmaatụ 2(2):
1. Li Z, Liu WD, Chen X, na Tal.Tetrahedron, 2013, 69, 3561-3564.
2. Ni Y, Li CX, Ma HM, na Tal.Appl Microbiol Biotechnol, 2011, 89: 1111-1118.
