Imine reductase (IRED)
Nkọwa dị mkpirikpi:
Banyere Imine reductase
ES-IRED: Otu klas nke enzymes na-eme ka mbelata C=N bond na CN bond.Ọ bụ nke redox enzyme, yana coenzyme NADPH maka njem hydrogen.Dị ka chiral mmasị nke ngwaahịa, ha nwere ike kewaa R-IRED na S-IRED.Syncozymes mepụtara 15 imine reductases (ọnụọgụ ES-IRED-101-ES-IRED-115), nke enwere ike iji ya mee ihe na mbelata regioselective na stereoselective nke imines iji kwadebe chiral amines.
Ụdị mmeghachi omume catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-mail:lchen@syncozymes.com
| Enzymes | Koodu ngwaahịa | Nkọwapụta |
| Enzyme ntụ ntụ | ES-IRED-101~ ES-IRED-114 | otu 14 Imine Reductase, 50 mg nke ọ bụla |
| 96 - Ngwa nyocha nke Enzyme nke ọma | ES-IRED-1400 | otu 14 Imine Reductase, 1 mg nke ọ bụla |
★ High mkpụrụ Specificity.
★ Strong chiral selectivity.
★ Ntughari dị elu.
★ Obere site-ngwaahịa.
★ Ọnọdụ mmeghachi omume dị nro.
★ enyi na gburugburu ebe obibi.
➢ Dị ka ọ na-adịkarị, usoro mmeghachi omume kwesịrị ịgụnye mkpụrụ, ngwọta nchekwa, enzyme, coenzyme, na coenzyme regeneration system.
➢ Ụdị ES-IRED niile dabara na ọnọdụ mmeghachi omume dị iche iche kwesịrị ka a mụọ ya n'otu n'otu.
➢ Mkpụrụ uche dị elu ma ọ bụ ngwaahịa nwere ike igbochi ọrụ ES-IRED.Agbanyeghị, enwere ike belata ihe mgbochi ahụ site na mgbakwunye nke mkpụrụ osisi.
Ọmụmaatụ 1 (Biosynthesis nke chiral 2-methyl pyrrolidine)(1):
Ọmụmaatụ 2(Biosynthesis of secondary amine)(2):
Ọmụmaatụ 3 (Mbelata nke cyclic imines)(3):
Debe afọ 2 n'okpuru -20 ℃.
Ejila ọnọdụ dị oke egwu na-akpakọrịta dị ka: oke okpomọkụ, elu / ala pH na nnukwu ihe mgbaze organic.
1. Scheller PN, Fademrecht S, Hofelzer S, et al.ChemBioChem, 2014, 15, 2201-2204.
2. Wetzl D, Gand M, Ross A, et al.ChemCatChem, 2016, 8, 2023-2026.
3. Li H, Luan ZJ, Zheng GW, et al.Adv.Synth.Catal.2015, 357, 1692-1696.
