Ketoreductase (KRED)
KRED sitere na SyncoZymes: E nwere ụdị ngwaahịa enzyme KRED 191 (Nọmba dị ka ES-KRED-101~ES-KRED-291) nke SyncoZymes mepụtara. Enwere ike iji SZ-KRED mee ihe nke ọma na mbelata mpaghara na stereoselective nke aldehydes, beta-ketone esters, α-ketone esters na ketones.
Ụdị mmeghachi omume catalytic:
| Enzymes | Koodu Ngwaahịa | Nkọwapụta |
| Ntụ ntụ Enzyme | Ntụ ntụ Enzyme | otu 187 Ketoreductases, 50 mg nke ọ bụla 187 ihe * 50mg / ihe, ma ọ bụ ọnụọgụ ndị ọzọ |
| Ngwa Nlele (SynKit) | ES-KRED-18100 | otu 181 Ketoreductases, 1 mg nke ọ bụla 181 ihe * 1mg / ihe |
★ Nkọwapụta ihe dị elu nke substrate.
★ Ịhọrọ chiral siri ike.
★ Ntugharị dị elu.
★ Ngwaahịa ndị na-adịghị mma.
★ Ọnọdụ mmeghachi omume dị nro.
★ Ọ dị mma maka gburugburu ebe obibi.
➢ A ga-enyocha enzyme maka ihe ndị dị na ya n'ihi na ha nwere nkọwapụta ihe dị na ya, wee nweta enzyme nke na-akwalite ihe ndị dị na ya nke nwere mmetụta kacha mma na-akpali akpali.
➢ Emetụla aka na ọnọdụ dị oke njọ dịka: oke okpomọkụ, oke pH dị elu/ala na ihe mgbaze organic nwere oke njupụta.
➢ Dịka ọ na-adịkarị, usoro mmeghachi omume kwesịrị ịgụnye ihe ndị dị n'ime ya, ihe ngwọta nchekwa, coenzymes (NAD(H) ma ọ bụ NADP(H)), usoro mmeghari coenzyme (dịka ọmụmaatụ glucose na glucose dehydrogenase).
➢ A ga-etinye KRED n'ime sistemụ mmeghachi omume ikpeazụ, mgbe pH na okpomọkụ gbanwere na ọnọdụ mmeghachi omume.
➢ Ụdị KRED niile nwere ọnọdụ mmeghachi omume kachasị mma dị iche iche, yabụ a ga-amụkwu nke ọ bụla n'ime ha n'otu n'otu.
Ihe atụ nke 1(1):
Ihe atụ nke abụọ(2):
1. Li Z, Liu WD, Chen X, na Tal. Tetrahedron, 2013, 69, 3561-3564.
2. Ni Y, Li CX, Ma HM, na Tal. Appl Microbiol Biotechnol, 2011, 89: 1111-1118.
